Song, Z. and Zhong, W. (2025) Research Advances in Subtype Classification and Diagnosis of Primary Aldosteronism. Journal of Biosciences and Medicines, 13, 1-11. doi: 10.4236/jbm.2025.136001 .

Increased aldosterone levels can cause hypertension. Lorundrostat was designed to reduce aldosterone levels by inhibiting CYP11B2, the enzyme responsible for its production. The Launch-HTN trial ...

sNDA accepted for Priority Review Lorundrostat (Mineralys Therapeutics) Highly selective aldosterone synthase inhibitor that reduces aldosterone levels by inhibiting CYP11B2 Treatment of ...

Lorundrostat is an aldosterone synthase inhibitor that reduces aldosterone levels by inhibiting CYP11B2, the enzyme responsible for its production. A previous phase 3 study, Launch-HTN ...

Lorundrostat was designed to reduce aldosterone levels by inhibiting CYP11B2, the enzyme responsible for its production. Lorundrostat has 374-fold selectivity for aldosterone-synthase inhibition ...

Lorundrostat is an orally-administered highly selective aldosterone synthase inhibitor that reduces aldosterone levels by inhibiting CYP11B2. The Launch-HTN trial (ClinicalTrials.gov Identifier ...

Lorundrostat is an aldosterone synthase inhibitor that reduces aldosterone levels by inhibiting CYP11B2, the enzyme responsible for its production. In previous studies, it demonstrated ...

dHUS Diagnostic Center, HUSLAB, Department of Pathology, Helsinki University Hospital and University of Helsinki, Helsinki, Finland eHeart and Lung Center, Helsinki University Hospital and University ...

Lorundrostat was designed to reduce aldosterone levels by inhibiting CYP11B2, the enzyme responsible for its production. Lorundrostat has 374-fold selectivity for aldosterone-synthase inhibition ...

Laekna announced that the FDA approved the Phase III clinical trial protocol for LAE002 (afuresertib, an AKT inhibitor) combined with LAE001 (a CYP17A1/CYP11B2 dual inhibitor) for the treatment of ...

Guangzhou Vinnocent Pharmaceutical Ltd. has divulged cytochrome P450 11B1, mitochondrial (CYP11B1; steroid 11-β-monooxygenase) and cytochrome P450 11B2, mitochondrial (CYP11B2; aldosterone synthase; ...