Harvard Medical School3d
Creating the World’s First CRISPR Medicine, for Sickle Cell Disease
In December 2023, through the development efforts of CRISPR Therapeutics and Vertex Pharmaceuticals, their decades-long ...
CRISPR Snips Away Extra Chromosomes, Offering New Hope for Down Syndrome Treatment
Scientists are exploring gene editing as a way to correct trisomy at the cellular level. Using CRISPR-Cas9, researchers successfully removed extra copies of chromosome 21 in Down syndrome cell lines, ...
Reprogramming compromised immune cells to fight cancer
Northwestern Medicine investigators have developed a new avenue to reprogram compromised immune cells to act against tumors, ...
The EMBO Journal13d
A CRISPR-Cas9 screen reveals genetic determinants of the cellular response to decitabine
A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...