Pinpointing the precise culprits behind harmful biological processes—such as excessive scarring (fibrosis) in organs like the ...

Abstract: The aim of our study was to investigate the use of targeted ultrasound microbubbles (MBs) for molecular imaging of murine endothelial CD81 expression. In the study, the anti-CD81-coated MBs ...

2 This algorithm uses 4 markers—CD81, CD5, CD23, and CD200—which the researchers claim provide high sensitivity and specificity in diagnosing CLL and distinguishing the disease from other ...

We further validated PG-EV tracking using dual-labeled EVs following two orthogonal labeling strategies: (1) Bioconjugation via surface amine labeling and (2) donor cell engineering via endogenously ...

Here, we identify CD81 as one of few surface proteins that are downregulated in HCV expressing hepatoma cells, discovering a functional role of CD81 beyond mediating HCV entry. CD81 was downregulated ...

Combining machine learning and experimental investigation, here we report CD81, a tetraspanin transmembrane protein known to be enriched in extracellular vesicles (EVs), as a newly identified driver ...

Reviewer #1 Evidence, reproducibility and clarity (Required): In this manuscript, Dr. Huiping Liu and colleagues investigate the role of CD81 in breast cancer metastasis, cancer stem cells, and ...

Here, we report 12 new surface molecules that can be used to study ASC biology, especially CD39 (NTPDase1), CD81 (TAPA-1), CD326 (EpCAM), and CD130 (gp130 or Oncostatin M Receptor) that can be used to ...

CD81 belongs to the evolutionary conserved tetraspanin family of proteins that form specialized membranal platforms that facilitate a vast array of cellular processes. However, little is known about ...