Corvus' soquelitinib shows promise in oncology & autoimmune fields, with Phase 3 PTCL data as a key catalyst. Click here to ...

"We were interested in how CD73, an emerging checkpoint molecule, is regulated and how we could improve immune therapy in the context of cancer," said Zhang, who was co-senior author of the study.

This is the second China-specific purchase by Sanofi in the last few months. In September, the French pharma acquired China rights to the CD73 antibody uliledlimab from I-Mab spinout TJ Biopharma.

On Wednesday, the popular “First-time disclosures” session of the ACS Spring 2024 meeting, in the Division of Medicinal Chemistry, offered a look behind the curtain of the drug development ...

The CD73 gene finds its home in the 6q14.3 region of human chromosome 6, encoding a protein comprised of 549 amino acid residues. CD73 functions as a glycosylphospholipase, residing on the cell ...

Jacobio Pharma announced it has entered into a clinical collaboration with Merck & Co., Inc., Rahway, NJ, USA to evaluate the combination of Jacobio’s CD73 monoclonal antibody JAB-BX102 in combination ...

“We are initially focused on CD73 due to its documented contribution to immune evasion through the production of immune-suppressive adenosine in the tumor microenvironment. We believe that a ...

Cidara’s lead oncology candidate, renamed CD421, targets CD73 in the adenosine pathway, which contributes to immune evasion in solid cancers by flooding the tumor microenvironment with adenosine ...