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Autologous HSCs were transduced with CD68-ET3-LV — a lentiviral vector including a new F8 transgene (ET3) with a myeloid-directed CD68 promoter — either without transduction enhancer (group 1 ...
A new study has evaluated the density and prognostic significance of CD68+ macrophages in the tubulointerstitium of patients with myeloperoxidase-antineutrophil cytoplasmic antibody-associated ...
Human CD68 and its murine homolog, macrosialin (Cd68), are glycosylated type 1 transmembrane proteins that belong to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and are ...
There are two major subtypes of LAMs, CD68+ M1 and CD163+ M2. M2 LAMs can be transformed from M1 LAMs, particularly in certain diffuse large B-cell lymphomas (DLBCL). While mantle cell lymphoma (MCL) ...
Association of gene expression with clinical outcomes in patients with renal cell carcinoma treated with pembrolizumab in KEYNOTE-427. This is an ASCO Meeting Abstract from the 2020 ASCO Annual ...
CD68 is a heavily glycosylated glycoprotein that is highly expressed in macrophages and other mononuclear phagocytes. Traditionally, CD68 is exploited as a valuable cytochemical marker to ...
NOTE. Right-most column indicates characteristics of final patient cohort of 90 for which data derived from all three biomarkers (FOXP3, CD68, and CD20) were available, which was not significantly ...
Effect of the oxLDL Binding Protein Fc-CD68 on Plaque Extension and Vulnerability in Atherosclerosis
To block oxLDL, we designed, expressed, and tested Fc-CD68, a soluble oxLDL binding protein consisting of human Fc and the extracellular domain of the human oxLDL-binding receptor CD68. Methods and ...
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