MDNA11 Phase 1/2 clinical trial on track for data readouts in second half of the year as a single agent and in combination with KEYTRUDA® at medical conferences and a planned KOL event ...

DAB–IL2 intoxicates sensitive eukaryotic cells by CD25 receptor-mediated endocytosis and is 100-times more potent in killing cells bearing the high-affinity isoform (CD25) of the IL-2 receptor ...

NK cells in particular target and destroy disease-causing pathogens, and detect and control the early signs of cancer. In ANKL, the NK cells are unable to perform their usual functions.

Space NK owner kicks off £300m-plus sale process Bankers at Raymond James have begun contacting prospective bidders for one of the UK's best-known high street beauty retailers, Sky News understands.

Nieto, Y., Banerjee, P., Kaur, I. et al. Allogeneic NK cells with a bispecific innate cell engager in refractory relapsed lymphoma: a phase 1 trial. Nat Med, 2025 DOI: 10.1038/s41591-025-03640-8 ...

About CAR-NK (PD-L1 t-haNK) PD-L1 t-haNK is a human, allogeneic, stable clonal NK cell line generated from the parental aNK cell line (NK-92), manufactured by the Sponsor under cGMP conditions.

We demonstrated a key role for antigen density and activating FcR in promoting depletion of tumour infiltrating regulatory T cells by anti-CTLA-4 antibodies (Arce Vargas et al., 2018) and a new ...

P!nk assembled her own powerful girl group at Thursday’s (Aug. 22) final night of the 2024 Democratic National Convention, joining daughter Willow Sage Hart, three backup singers and one ...

Background: AU-007 is a computationally designed human mAb that binds interleukin-2 (IL-2) on its CD25 binding epitope. AU-007 bound IL-2 cannot bind trimeric (CD25, CD122, CD132) IL-2 receptors ...

The long-standing owner of Space NK, the high street beauty retailer, is preparing to put it up for sale with a price tag of more than £300m. Sky News has learnt that Manzanita Capital, a private ...

This leads to tumor lysis, as suggested by the increased expression of IL-12Rβ2 and enhanced CD25 expression in NK cells, though the latter may be due to IL-2 signaling.