And one of the ones that was highlighted at this particular meeting was the urinary soluble CD163, which I think adds or sort of sheds light on the fact that sparsentan, which is dual endothelin ...

By altering the CD163 gene, Genus has made pigs resistant to porcine reproductive and respiratory syndrome (PRRS). This is a highly contagious viral disease that causes widespread losses for pig ...

“In addition to reducing proteinuria, treatment with sparsentan also resulted in rapid and sustained reductions in urinary soluble CD163, a biomarker for activated macrophages,” Cheung said.

Macrophage receptor CD163 is an essential component of this system that aids in removing free hemoglobin from the circulation. This process helps in maintaining the body's equilibrium by ...

CD163 might not be the most exciting name in the world, but behind it lies one of the body’s most important defence receptors, which steps in when red blood cells break down and release harmful ...

“These observations were further supported by reductions of CD163, a validated urinary biomarker, also indicating an impact on immune cell homing and trafficking to the kidney.” In both clinical ...

The study introduces an innovative tracer targeting CD163, a molecular receptor on tumor-associated macrophages—immune cells that support tumor growth and protection. The tracer is based on ...

Commercializing the science conducted by the University of Missouri in 2015, Genus’ technique deleted a receptor known as CD163 that allows the virus to establish an infection. A U.K.-based ...