My research is focused on understanding neuroendocrine and age associated changes in immune function and inflammatory responses. Immune function decline with age, resulting in increased illness and ...

The level of CD107a on the NK cells was analyzed prior to and following coculturing with K562 cells to evaluate the developed NK cells further. CD107a expression was determined to increase ...

HIV-specific T cell responses were defined as the difference in frequency of cytokine/CD107a+ cells between HIV stimulated and nonstimuated cells. Frequencies of CD4 or CD8 T cells that were single or ...

Decision letter after peer review: Thank you for submitting your article "Single-cell CD8 + dynamics uncover the reduction of CD107a TIGIT+ memory HIV-1-specific cells in PLWH over a decade of ART" ...

NK cell degranulation was quantified by measuring CD107a surface expression using flow cytometry. A. Representative histograms (overlay) displaying CD107a expression on NK cells after culture with the ...

Conventional as well as emerging diagnostic tests, including cytokines and chemokines (eg, IFNγ, IL-18, CXCL9, CXCL10) and flow cytometry (eg, CD107a, perforin, T-cell activation profiles), are ...

As can be seen in Fig EV1D, NK cell degranulation (LAMP1, CD107a expression) was higher in YTS‐2DL1 that were transfected with a combination of SHP‐1 and Cbl siRNAs and interacted with 221‐Cw4 cells, ...

For intracellular staining of cytotoxicity-related molecules, 3 × 10 5 fresh isolated PBMCs were stained by fluorochrome-conjugated monoclonal antibodies against Vδ1, Vδ2, and CD107a for 30 min at 4°C ...

Strikingly, impaired degranulation of cytotoxic T-lymphocytes (CTL) and natural killer (NK)-cells was detected in CD107a-analyses. The affected patient was treated with HLA-matched unrelated alloHSCT, ...

The aim of this study was to investigate the activation marker CD314 (NKG2D) and CD107a (LAMP-1) on cytotoxic CD8 +T cells in patients with systemic lupus erythematosus. Methods Peripheral blood of ...

Anti-CD107a antibody was added in the presence of monensin for 4 hours. For IL-12/18 stimulation, spleen cells were incubated with 25 ng/mL IL-12 and 20 ng/mL IL-18 (R&D systems) for 4 hours in the ...