The manuscript addresses the 3D chromatin architecture in monocytes from patients with alcohol-associated hepatitis and its relationship to enhanced transcription of innate immune genes. While the ...

The liver, located in the upper right side of the abdomen, is the body’s largest organ and one of the most important. The liver performs hundreds of vital functions, including converting ...

What Is an Inflamed Liver? Inflammation is the body's way to heal an injury or damaged cells. In the liver, this injury can be caused by many things, including an infection, toxins, or the buildup ...

Cirrhosis is a condition in which scar tissue gradually replaces your healthy liver cells. It usually happens over a long period, often due to hepatitis, alcohol use disorder, or metabolic ...

Here, we investigated the impact of MAGL on inflammation and fibrosis during chronic liver injury. Conclusion MAGL is an immunometabolic target in the liver. MAGL inhibitors may show promising ...

Akero Therapeutics reported Monday strong results from a nearly two-year, placebo-controlled study showing its drug efruxifermin reversed liver scarring in patients with cirrhosis caused by the ...

Elevated liver enzymes can occur for many reasons. Most often, elevated liver enzymes are temporary and resolve on their own without treatment. Occasionally, elevated liver enzymes require additional ...

Lung cancer liver metastases are tumors that form in the liver from cancer cells that have broken away from the primary cancer and spread through the blood or lymphatic system. The liver is a common ...

What is a liver biopsy? A liver biopsy is a test used to diagnose liver conditions. Tissue samples are removed from your liver and checked under a microscope for signs of damage or disease. A liver ...

What is a liver transplant? A liver transplant is surgery to replace a diseased liver with a healthy liver from another person. A whole liver may be transplanted. Or part of a liver may be ...

Liver cells were stained with the indicated fluorescent mAbs ... In group A, C1QC macro expressed CCL3 and CCL4 signaling to cognate receptors CCR5 on LTB-MAIT and GZMB-MAIT cells, and SLC40A1 macro ...