The research team found that high levels of a protein, the chemokine receptor CCR1, are linked to worse outcomes in MM patients, particularly as the disease progresses. CCR1 is a receptor ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Concurrent analysis of whole-genome DNA ...

ST chemokine (CCL2/MCP-1, CCL5/RANTES, CCL7/MCP-3, CCL8/MCP-2, CCL14/HCC-1, CCL15/HCC-2, CCL16/HCC-4), chemokine receptor (CCR1, CCR2b, CCR5, CXCR4), and CD13 expression was analysed by ...

Department of Chemistry and Pharmacy, Medicinal Chemistry, Friedrich-Alexander-University Erlangen-Nürnberg, Nikolaus-Fiebiger-Straße 10, Erlangen 91058, Germany Immuno-Pharmacology and Interactomics, ...

In silico tumor immune microenvironment (TiME) analysis of non-small cell lung cancer (NSCLC) to inform clinical development of CDR404: A first-of-its-kind MAGE-A4 targeted T-cell engager. This is an ...

Kirin has been granted a patent for a monoclonal antibody that binds to human CCR1, inhibiting its activation by CCL15. The antibody can be used in therapeutic and diagnostic agents for CCR1-related ...

Kyowa Kirin has been granted a patent for a monoclonal antibody that binds to human CCR1, inhibiting its activation by CCL15. The patent covers specific antibody sequences and their fragments, along ...

Besides, HAVCR2 was positively correlated with most known immunomodulatory genes, especially CCR1, CCR5, PDCD1LG2, and CD86. Totally, our work provided new insights and theoretical basis for HAVCR2 as ...

Moreover, M2a hMdɸs express several CCRI (C-C chemokine receptor type 1) ligands. Importantly, CCR1 was upregulated in Müller cells in models of retinal injury and aging, and CCR1 expression was ...

F5H n.d. 35.0 ± 7.2 722 ± 9.5 2,462 ± 281 ccr1 81.1 ± 6.1 280 ± 33.6 n.d. 38.3 ± 12.8 ccr1 fah1-2 93.0 ± 11.4 280 ± 39.3 n.d. n.d. ccr1 C4H:F5H n.d. 45.1 ± 11.9 486 ± 64.5 2,443 ± 116 cadc cadd 627 ± ...

Chemokines belong to a family of proteins called the cytokines and are involved in initiating and guiding the recruitment and migration of immune cells to sites of infection or damage. Chemokines ...