no. Q711). The TNF-α, IL-1β, IRF1, CASP1, and GAPDH primers were synthesized by Sangon Biotech (Shanghai, China). Supplementary Table S3 lists the sequences and associated target species. The FC was ...

EBNALP inactivation alters enhancer–promoter interactions, resulting in decreased CCND2 and increased CASP1 and BCL2L11 expression. Mechanistically, EBNALP interacts with and colocalizes with the ...

Cytokine secretion was measured in the supernatant of human monocytes using commercially available ELISA kits for IL-6, IL-8, IL-1β, MCP-1 (monocyte chemoattractant protein-1), and Casp1 (caspase-1) ...

Intracellular caspase-1 (Casp1) activity in nigericin- and LPS-activated human peripheral blood mononuclear cells (PBMCs) was evaluated. Next, the team investigated whether JT002 blocked ASC ...

Our results identified a novel macrophage-like subset called monocytic hemocytes 2 (MH2) defined by the expression of certain marker genes, including Nlrp3 and Casp1. This subtype of shrimp hemocytes ...

WGCNA indicated that the turquoise and blue modules were the critical modules. CASP1, SERPINA1, and CCL2 have been identified as the hub autophagy-related genes of active UC, after combining DEGs and ...

The NLRP3 inflammasome is a multimeric protein complex constituted by NLRP3, Asc and Capase-1 (Casp1). It triggers an inflammatory response by releasing the pro-inflammatory cytokines IL-1β and IL-18.

When indicated, cells were primed with LPS for 2 h prior to stimulation. αSS and αLS indicate the use of a small subunit‐ and a large subunit‐specific CASP1 antibody, respectively. Lys = lysate, SN = ...

Regions corresponding to the string-of-pearls, transition, and mature stages are marked. Dynamics of LAC3-eGFP and CASP1-mRuby3 accumulation at the string-of-pearls stage. Asterisks indicate the gap ...