The parents of a seven-year-old boy who died in a clinical trial have spoken of their "indescribable" pain. Ender Nihat, from Essex, suffered organ failure after receiving chemotherapy during ...

Findings showed the hazard ratio for OS compared with busulfan was 0.67 in all randomized patients. The Food and Drug Administration (FDA) has approved Grafapex ™ (treosulfan) for injection with ...

GRAFAPEX™ (treosulfan) with fludarabine is FDA-approved for AML and MDS patients undergoing alloHSCT, showing improved overall survival compared to busulfan. Common side effects include ...

The regimen was evaluated in MC-FludT.14/L Trial II, which compared treosulfan versus busulfan alongside fludarabine in 570 patients. Eligible patients included adults with AML or MDS, a Karnofsky ...

Clinical trial results showed improved overall survival with treosulfan compared to busulfan. Common adverse events include musculoskeletal pain, stomatitis, and nausea, with some severe ...

Beam Therapeutics has acknowledged the death of a patient in a Phase I/II trial assessing the base editing therapy candidate BEAM-101—a death the company said was likely caused by the ...

Before the exa-cel infusion, patients underwent myeloablative conditioning with pharmacokinetically dose-adjusted busulfan. The primary end point was freedom from severe vaso-occlusive crises for ...

Details concerning the Busulfan (2mg) medication encompass its pricing as well as its availability in various forms, including tablets, capsules, syrups, creams, gels, ointments, liquids ...

We specialize in busulfan TDM, providing individualized drug exposure targeting for patients from over 75 medical institutions in the U.S. and Canada. Therapeutic drug monitoring (TDM) is the ...