In addition to rod photoreceptor loss, many mutations in rod photoreceptor-specific genes cause degeneration of other neuronal types. Identifying mechanisms of cell–cell interactions initiated ...

Atsena Therapeutics, a clinical-stage gene therapy company focused on bringing the life-changing power of genetic medicine to reverse or prevent blindness, today announced that safety and efficacy ...

RS1 is localized to the extracellular surface of rods, cones, and bipolar cells. XLRS is characterized by schisis, or abnormal splitting of retinal layers, which causes impaired visual acuity that is ...

notably impacting rod photoreceptors and specific inflammatory cell subsets. Differential gene expression analysis of rods, cones, and bipolar cells (BCs) identified a common upregulation of pathways ...

A critical component of the hydrogen fuel cell is the bipolar plate, which facilitates the electrochemical processes that produce electricity. Bipolar plates distribute reactant gases — hydrogen at ...

This study demonstrates the critical role of Afadin on the generation and maintenance of complex cellular layers in the mouse retina. The data are solid, which provides important insights into how ...

However, the study provides limited new insights into the relationship between retinal lamination defects and overall retinal function. Neural lamination is a common feature of the central nervous ...

Inside the retina, there are millions of special sense receptors called rods and cones. The rods see the shapes of things, picking out black, white and shades of grey, and the cones see the ...

School of Integrated Circuits, Southeast University, Sipailou 2, Nanjing 210096, P. R. China School of Microelectronics, Northwestern Polytechnical University, Xi’an, Shaanxi 710072, P. R. China ...

Strong immunostaining was observed in numerous amacrine cell bodies and in all horizontal cell bodies in the proximal and distal INL, respectively. Some bipolar cells were also weakly immunostained.