It's linked to mutations in the BMPR1B or GDF5 genes. Type A3. With this type, only the middle bone of your little finger is shortened. It's tied to mutations in the HOXD13 gene.

Iregene Therapeutics (Suzhou) Co. Ltd. has identified pyrazolecarbonyl piperazinone compounds acting as bone morphogenetic protein receptor type-1B (BMPR1B) inhibitors reported to be useful for the ...

During endochondral ossification, chondrocytes are formed after the condensation of mesenchymal stem cells and finally create a scaffold for osteoblastogenesis. For life-long cartilage homeostasis, ...

We found additional CPSF6-regulated PASs with similar twin UGUA motifs in human and experimentally validated the twin UGUA motif functionality in BMPR1B, MOB4, and BRD4-L. Importantly, we showed that ...

The role of BMPR1B gene fusions and their protein products in cancer biology remains unknown because, to date, standardized classification guidelines for inherited conditions arising from the loss ...

The BMPR1B and BMP15 genes are well known for their considerable associations with prolificacy in sheep. These genes may also affect fertility or prolificacy in other species, including human. This ...

when I was running infercnv，I set parameters as follows: infercnv_obj = CreateInfercnvObject (raw_counts_matrix=expFile, annotations_file=groupFiles, delim="\t ...

BMPR1B was a direct target of miR-1306 in ovine granulosa cells To investigate whether the BMPR1B gene of Hu sheep is targeted by miR-1306, we performed luciferase assays using wild-type and ...

The BMP pathway has been known to play a role in NPC function. Specifically, BMPR2 is a type II receptor that heterodimerizes with BMPR1a or BMPR1b, and is responsible for transducing BMP signaling ...

Pulmonary arterial hypertension (PAH) is a type of pulmonary hypertension characterized by remodeling (thickening and narrowing) of the small pulmonary arteries, which results in increased pulmonary ...