This study provides useful information on the impact of Lamin A/C knockdown on gene expression using RNA-Seq analysis. In addition, the impact of Lamin A/C knockdown on telomere dynamics is explored ...

Dettifoss waterfall, Jökulsárgljúfur National Park, Iceland. 45 metres high and 100 metres wide, Dettifoss is Europe's most powerful waterfall. Up to 500 cubic metres of water thunder over the edge ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Breast cancer is a leading cause of mortality ...

A 58-year-old Black man with hypertension and diabetes mellitus presents to the clinic with a growing, solitary nodule on his lower back that has been present for the past year. He lives alone and ...

ATP6AP1 and ATP6AP2, which we previously identified to be recurrently altered in granular cell tumors (GCTs), encode for accessory proteins of the vacuolar (V)-ATPase, which controls endosomal ...

Background: A rare X-linked hereditary condition known as ATP6AP2-congenital disorder of glycosylation (ATP6AP2-CDG) is caused by pathogenic variants in ATP6AP2, resulting in autophagic misregulation ...

The kidneys generate about 180 l of primary urine per day by filtration of plasma. An essential part of the filtration barrier is the slit diaphragm, a multiprotein complex containing nephrin as major ...