Determining what molecular interactions are present between an antibody and its antigen can define the epitope ... scripts output a heat map for the average per-residue pLDDT and a bar-chart that for ...

Peptide antigen-associated IgG levels were significantly lower in drug-naïve patients with first episode psychosis compared to control individuals.

A team of biomolecular engineers, pathologists, and internal medicine specialists at the University of Texas Medical Branch, ...

Malaria remains a significant global health challenge, causing over 600,000 deaths annually despite existing prevention and treatment measures. Current vaccines and monoclonal antibodies (mAbs) ...

and B-cell maturation antigen (BCMA). Developed using Simcere’s T-cell engager polyspecific antibody technology platform, the therapy has demonstrated strong T-cell cytotoxicity against MM cells.

(2) These cells are activated using anti-CD3/CD28 antibodies to stimulate their proliferation. (3) Genetic modification of the T cells is performed by inserting the CAR gene, enabling them to ...

SIM0500 is currently in Phase 1 clinical trials in patients with relapsed or refractory multiple myeloma (MM), in both China and the U.S. SIM0500 is a humanized trispecific antibody that targets ...

This approach preserves the native context of the presented antigens, streamlining the discovery process and identifying more biologically relevant hits. The Nanovial Multicell Antibody Discovery ...

A new study shows how an anticancer drug triggers an "outside in" signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals a new signaling mechanism ...