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The presence of MYC translocation and high MYC mRNA expression have recently been associated with poor OS in patients with DLBCL treated with R-CHOP, raising questions about optimal management of ...
New York City mayoral race front-runner Andrew Cuomo was forced to fend off a volley of attacks from his Democratic primary rivals in a debate.
Applying a dual-engine approach that combines generative chemistry with advanced physics-modeling module AlChemistry, the research team identified and validated novel compounds with sub-micromolar ...
Breast cancer is the most frequent malignancy among women worldwide, and all subtypes of breast cancer involve upregulation of the c-Myc gene, making it a compelling therapeutic target. G-rich regions ...
Dr. Chidiebere Awah, MD, PhD, CEO of UTR Therapeutics Inc. shares his approach on revolutionizing cancer care NEW YORK, May 08, 2025 (GLOBE NEWSWIRE) -- UTR Therapeutics Inc (UTRx Inc.), a drug ...
This results in high fidelity targeting of c-MYC driven tumor cells but with excellent safety and tolerability in normal healthy cells both in-vitro and in-vivo. Our first-in-human Phase 1 trial ...
Follow the latest developments as Republicans craft a budget and move it through the reconciliation process.
When researchers inhibited RBM42 in mice, the cells kept producing Myc mRNA, but not Myc protein. “Think about having a lot of Legos,” Ruggero said. “You put them all together.
None of the sampled non-small cell lung cancer patients had high L- or N-MYC. Levels were higher in small cell lung cancer, 31%, and high-grade neuroendocrine tumors, 17%, but the figures still ...
When MYC ecDNA levels soared, cells morphed into more aggressive, solid structures—losing their more organized, gland-like architecture. “Here, we show that extrachromosomal DNA ...
24-year-old eats a 65-cent breakfast every day, skips salon visits and has saved $90K—she’s part of Gen Z’s FIRE movement and plans to retire by 40 ...
Infinite Roots (IR), formerly Mushlabs, is a German biotech company that has been plying the furrow of Mycelium, the material coming from fungi, which has ...