Scientists have identified a biomarker for Alzheimer's that may help doctors spot the early signs of protein buildup in the ...

Amyloid Precursor Protein’s Roles Outside of Alzheimer’s Disease Amyloid ... ultimately, a difference in cortex structure between mutant mice and controls. A recent study the lab carried out using ...

"We've demonstrated that the unique W-shaped structure of amyloid fibrils ... by mutations to the gene that encodes for the amyloid precursor protein," explains Yoshitaka Ishii of the RIKEN ...

Progress in deciphering the fundamental biological mechanism of Alzheimer's disease (AD) is proceeding at an impressive pace. A consensus has emerged among many investigators that cerebral ...

Here we demonstrate that a modest increase in astroglial TGF-β1 production in aged transgenic mice expressing the human β-amyloid precursor protein (hAPP) results in a three-fold reduction in ...