A model illustrating the function of ALDH3A1 regulating ferroptosis in SCCs. ALDH3A1 is overexpressed by TP63 transcriptional regulation in squamous cell carcinoma and plays an anti-ferroptosis ...

Figure 8: Regulation of ALDH3A1 and NECTIN4 by p53. Researchers Jessica J. Miciak, Lucy Petrova, Rhythm Sajwan, Aditya Pandya, Mikayla Deckard, Andrew J. Munoz, and Fred Bunz from the Sidney ...

The first, ALDH3A1, helps detoxify harmful substances and may impact cancer cell resistance to oxidative stress. The second, NECTIN4, is a protein found in many aggressive cancers, including ...

In this study, the researchers found that the protein ALDH3A1, known for its role in detoxifying harmful substances in the body, is overactive in SCC cells. This protein acts as an "antioxidant ...

These similar cell-type proportion suggested the low individual heterogeneity of AK samples. To explore the relationship between ALDH3A1 expression and UV irradiation, HaCat cells were subjected to ...

5) Some of the claims regarding in vitro and in situ validation of candidate genes including MAGEA4, ITGA6, IGFBP, and ALDH3A1 are not supported by the data. If these data cannot be provided, revise ...

We also found important genes related to smoking phenotype, such as NQO, HSPA1A, ALDH3A1. As for DM2 analysis, our results suggested 9 pathways were significantly expressed, including typical pathways ...

Department of Molecular Biology and Genetics, Faculty of Health Sciences, Democritus University of Thrace, Alexandroupolis, Greece Aldehyde dehydrogenase 3A1 (ALDH3A1) by oxidizing medium chain ...