Mechanistically, targeting DUSP22 suppressed FOXO3a, a master regulator of skeletal muscle wasting, via downregulation of the stress-activated kinase JNK, which occurred independently of aberrant Akt ...

State Key Laboratory of Food Science and Resources, Jiangnan University, Wuxi, Jiangsu 214122, China School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China National ...

PKB/Akt is activated via PI3-kinase and PIP3, which in turn, are controlled by the phosphatase PTEN. In addition, the stress kinase JNK has been shown to phosphorylate PKB at the onset of reperfusion.

Notably, pretreatment of IGF-1, an Akt activator, attenuated the diosmetin-induced apoptosis. Furthermore, pretreatment with SP600125, a JNK inhibitor, significantly reduced the protein level of LC3B, ...

Protein kinase Akt was upregulated in human PAH PAVSMC in a sirtuin 7 (SIRT7)- and c-Jun N-terminal kinase (JNK)-dependent manner. Pharmacological inhibition of Akt down-regulated ACLY and ACC, ...

Proteintech), p-AKT (AF0832, Affinity), JNK (66210-1-Ig, Proteintech), p-JNK (AF3318, Affinity), p53 (60283-2-Ig, Proteintech), and p-p53 (AF3075, Affinity)] overnight at 4°C following an antigen ...

Anna Kaiser, the founder of AKT, sold her brand to Xponential Fitness before the pandemic. Now she wants it back. By Julie Satow Anna Kaiser, a celebrity fitness trainer, is known for dispensing ...

Silencing of TRPM7 decreased the migration and invasion ability of T24 and UMUC3 cells. The phosphorylation of Src, Akt, and JNK (c-Jun N-terminal kinase) was also suppressed by TRPM7 silencing. Src, ...