GAS2 is a cytoskeletal regulator that interacts with both F-actin and microtubules. Here, cryo-EM structures of GAS2 domains bound to F-actin and microtubules and biochemical experiments reveal the ...

Actin is a highly abundant protein that controls ... of biochemical strategies and electron cryo-microscopy (cryo-EM). The breakthrough, published in the journal Science, can help us explain ...

who served as co-first authors - analyzed actin filaments using cryo-EM. With this high-resolution imaging technique, a researcher obtains many thousands of snapshots of a target molecule ...

who served as co-first authors -- analyzed actin filaments using cryo-EM. With this high-resolution imaging technique, a researcher obtains many thousands of snapshots of a target molecule ...

Actin isoforms organize into distinct networks that are essential for the normal function of eukaryotic cells. Despite a high level of sequence and structure conservation, subtle differences in their ...

In a video announcing the fragrance, Lambert sprays the Velvet Rodeo Eau de Parfum while her song "Actin' Up" from her 2022 album, Palomino, plays. She explains that the fragrance was inspired ...

Those changes cause many neurological disorders. Here, we will review direct visualization of ABP and actin using various electron microscopy (EM) techniques, super resolution microscopy (SRM), and ...

1 Instituto de Ciências Biomédicas Abel Salazar (ICBAS), Universidade do Porto, Porto, Portugal 2 Neurodegeneration Group, Instituto de Biologia Molecular e Celular (IBMC) and Nerve Regeneration Group ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Cellular studies of filamentous actin (F‐actin ...

These structures show how conformational changes during actin assembly promote ATP hydrolysis and faster growth at one end of the filament than the other. We used cryo-electron microscopy (cryo-EM) to ...

The Actin-Binding Site of Myosin Is Structurally Diverse ... and purification and experimental conditions and methods for structural determination by cryo-EM are described in SI Materials and Methods.