While autophagy is relevant to many biological processes and often serves as a gatekeeper of homeostasis, when something goes wrong it can either lead to disease or be activated to fight against it.

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Germ cells are unique in engendering ...

1 Reproductive Medicine Center, Boai Hospital of Zhongshan, Zhongshan, Guangdong, China 2 The Second School of Clinical Medicine, Southern Medical University, Guangzhou, Guangdong, China Introduction: ...

Chapter Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to ...

Spermatogenesis is a crucial biological process that enables the production of functional sperm, allowing for successful reproduction. Proper germ cell differentiation and maturation require tight ...

ABSTRACT: Objective: To analyze the application value of combined detection of sperm quality, sex hormone and ovulation in the diagnosis of infertility. Methods: The study was conducted from June 2021 ...

In this study, we generated hamsters without acrosin, the major acrosomal protease, to examine its role in both in vivo and in vitro fertilization. Surprisingly, mutant male hamsters were completely ...

The authors note that on page 2517, left column, third full paragraph, line 25, “(500 V/cm, 50-ms duration, 5-ms intervals)” should instead appear as “(500 V/cm, 5-ms duration, 50-ms intervals).” Note ...

Each group received the following examination such as semen analysis (including semen volume, sperm concentration, progressive motility, total motility, round cell concentration), acrosin activity, ...

Cancer/testis (CT) antigens are proteins whose expression is normally restricted to germ cells yet aberrantly activated in tumors, where their functions remain relatively cryptic. Here we report that ...