There are only 4 reports about the role of ATP1A2 gene in the pathogenesis of AHC [5–8]. The ATP1A2 missense mutations are known to be responsible for different types of familiar hemiplegic migraine.

Among them, pathogenic variants in ATP1A3 are responsible for almost 80% of cases. The aim of our study was to present a patient with de novo ATP1A2 mutation as the primary cause of AHC and to study ...

Migraine is a neurological disorder characterized by severe headache pain, nausea, dizziness, and sensitivity to light and ...

The genes believed to play a role in MBA are the ATP1A2 gene or the CACNA1A gene. Scientists further think abnormalities of nerves and/or altered blood flow to the brainstem, as well as the occipital ...

carrying a p.H916L mutation in ATP1A2 gene. Methods We assessed neurovascular changes with time in the affected cerebral hemisphere corresponding to aura symptoms during the acute phase of HMPA.

Gene mutations associated with familial hemiplegic migraine include: FHM1, caused by mutations in the CACNA1A gene located on chromosome 19 FHM2, caused by mutations in the ATP1A2 gene located on ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Transcriptomic and biochemical analyses of ...

A 2021 study confirmed abnormalities in the ATP1A2 gene in a family with familial hemiplegic migraine type II. The same gene contributes to anxiety. According to older reports from 1999 ...

Research has also shown 35 percent of patients with mutations in a second hemiplegic migraine ion channel gene, ATP1A2 – which is linked to hemiplegic migraine, ataxia, epilepsy, and other seizures ...

Research has also shown 35% of patients with mutations in a second hemiplegic migraine ion channel gene, ATP1A2 – which is linked to hemiplegic migraine, ataxia, epilepsy and other seizures and ...

PPI network and Cytoscape showed that ATP1A2, PLN, KCNMA1, and SCNN1B were four central DEGs. GO analysis results revealed that DEGs were involved in negative management of myocardial contraction, ...