Using HeLa cells and primary hippocampal neurons, we demonstrate that surface removal of TLN involves internalization events mediated by the small GTPase ADP‐ribosylation factor 6 (ARF6), and its ...

However, these vapes are rich in the ARF6 protein, which is associated with lung tissue harm. More people are vaping instead of smoking nowadays. The young see it as a cooler alternative than ...

In the cells exposed to nicotine-free vape fluid, the team identified an unusual abundance of a particular protein called ARF6, which looks to be responsible for lung tissue damage in the lab. This ...

Despite being considered a safer alternative to smoking, vaping, even without nicotine, poses risks. The study identifies a protein, ARF6, linking nicotine-free vape exposure to vascular damage. A new ...

This damage is similar to those found in patients with lung injury. Data analysis revealed that a protein, ARF6, which was not previously thought to be linked to smoking or lung injury but is ...

Study findings “indicate that ARF6 plays a critical role in [brain-CNS barrier] function … and provide preclinical rationale for targeting ARF6 as a therapeutic approach to treat MS,” its ...

Thus, we used small interference RNA to investigate the impact of ARNO on the pathological migration and inflammatory responses of murine SFs, revealing a fully functional ARNO-ARF6 pathway which can ...

Incidence of ERBB gene fusions (EGFR, ERBB2, ERBB4) across tumor types. This is an ASCO Meeting Abstract from the 2021 ASCO Annual Meeting I. This abstract does not include a full text component.

Different populations of REs, particularly those formed by Rab11, Rab35, and Arf6, are associated with a myriad of signaling proteins. In this review, we discuss the cumulative evidence suggesting the ...

As a result, research has also focussed on targeting ARF6, another necessary component of Gα protein signaling. A promising hope for G protein targeting in the future Until these studies ...

The release of EVs occurs when cocaine causes dissociation of the Sig-1R from ADP-ribosylation factor (ARF6), a G-protein regulating EV trafficking, leading to activation of myosin light chain kinase ...