Parkinson's disease is a neurodegenerative disease ... Validation results showed that the antioxidants activate the AMPK enzyme (adenosine monophosphate-activated protein kinase), an intracellular ...

View Full Profile. Learn about our Editorial Policies. PINK1 triggers a downstream cascade of events that leads to mitophagy—a process by which the cell clears away any mitochondria it doesn’t need. 4 ...

During the healthy aging process, the microbial-derived metabolite phenylacetylglutamine (PAGln) drives host cellular senescence by inducing DNA damage and mitochondrial dysfunction via ...