drives host cellular senescence by inducing DNA damage and mitochondrial dysfunction via adrenoreceptor–AMPK signaling. Low-dose adrenoreceptor blockade treatment mitigates this PAGln-induced ...

Johns Hopkins University School of Medicine researchers have discovered a dual regulatory mechanism safeguarding ...

Researchers from the Mitochondrial Medicine Program at Children's Hospital of Philadelphia (CHOP) have better characterized a ...

Mike Tyson is setting the record straight amid rumors he has Parkinson’s Disease following comments made by Jake Paul. The heavyweight boxing legend took on the YouTube personality-turned ...

A research collaboration has found that besides regulating the fusion of mitochondria, Mitofusin 2 also ensures protein quality control. This discovery could open up new routes to treating ...

A comprehensive analysis has identified novel enhancers associated with neuronal development and disease.

An enzyme of increasing importance in mitochondrial and metabolic dysfunction is AMPK (AMP-activated protein kinase). AMPK plays an important role in cellular energy homeostasis and is a crucial ...

A by-product of cholesterol plays a "pivotal" role in Parkinson’s disease, according to new research. The metabolite is critical in the development of the neurodegenerative condition in mice ...