Researchers from The University of Osaka reveal the mechanism by which a common air pollutant impairs our airway defense ...

A new study suggests that activating an enzyme known as ALDH1A1 could help protect the lungs from air pollution, particularly ...

New research has identified the mechanism by which air pollution damages the lungs’ self-cleaning system, leaving us ...

Air pollution is the second leading risk factor for death globally, with most of the world population subject to harmful air ...

Air pollution is the second leading risk factor for death globally, with most of the world population subject to harmful air ...

Using a combination of molecular analysis, microscopic imaging, and electrophysiological techniques, the researchers pinpointed two enzymes, SIRT2 and ALDH1A1, as central to the surge in GABA ...

Through molecular analysis, microscopic imaging, and electrophysiological techniques, they identified SIRT2 and ALDH1A1 as key enzymes responsible for the elevated GABA levels in astrocytes affected ...

AB8939 is a new synthetic molecule which jointly targets cancer cells, by destabilizing the microtubules essential for cell division, and cancer stem cells, by inhibiting enzymes (ALDH1A1 and ALDH2) ...

They discovered that two enzymes—SIRT2 and ALDH1A1—are strongly linked to the extra GABA production. SIRT2, in particular, was found in higher amounts in both mouse models of Alzheimer’s and ...

After a series of processes, they managed to isolate two enzymes considered key in this action that are SIRT2 and ALDH1A1. The first was detected at very high levels in both mice and humans after ...

Using advanced lab techniques on mice and human brain samples, they discovered that two enzymes—SIRT2 and ALDH1A1—play a critical role in GABA overproduction in Alzheimer’s-affected brains.