The research was published on Chemical Biology & Drug Design. The MYC protein is a well-established driver in up to 70% of human cancers, but has long been considered “undruggable” due to the ...

Here are the latest planning applications submitted to Basildon Council, featuring proposals for home extensions, commercial changes, and new residential developments across the borough. Among the ...

Every week, Preston City Council decides whether to approve or reject planning applications for everything from new estates and house extensions to shop conversions and industrial developments ...

MYC is dysregulated in nearly 70% of human cancers, where it influences a vast network of biological processes including cell cycle control, metabolism, apoptosis, angiogenesis, and immune evasion.

Pioneered by Dr. Chidiebere Awah MD, PhD, our CEO and Principal Investigator, UTRxM1-18 targets oncogenic c-MYC by recognizing specific motifs and switching the ribosome machinery from a ...

Almost 2,000 properties have been affected by a power cut near Barnstaple this afternoon (Thursday, May 8). At 1.01pm, a power outage was reported in the EX32 postcode. Several hundred properties ...

Follow the latest developments as Republicans craft a budget and move it through the reconciliation process. Senate Democratic Leader Chuck Schumer (NY) and others held a news conference following ...

Inhibiting RMB42 disrupted production of Myc proteins in pancreatic cancer cells. This approach could curtail the growth of several cancer types. A review paper published last year in European ...

Further afield, one person shared: “Knaresborough is only twenty minutes away by train and the Nidd Gorge (HG5 0BH) is beautiful woodland.” Another agreed: “Further a field, I would ...

The wholly owned MRT-2359 is Monte Rosa’s attempt to exploit a vulnerability of MYC-driven tumors. Believing the tumors are dependent on GSPT1, the biotech designed a molecule to drive ...

In healthy cells, a protein called MYC helps guide the process of transcription, in which genetic information is converted from DNA into RNA. But when cells turn cancerous, they start to produce way ...