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Here the authors show that the snoRNA Snord67 promotes lymph node metastasis of breast cancer cells through guiding modifications of the spliceosome and regulating the splicing landscape.
Here, the authors identify a snoRNA that not only guides ribosomal RNA 2’- O-methylation but also modulates the activities of RNA-binding proteins involved in fission yeast gametogenesis.
These intronic sequences can escape the debranching enzyme and accumulate as lariats. Stable lariats bearing a snoRNA, or slb-snoRNA, are associated with snoRNA binding proteins but do not guide ...
In Xenopus cells, a guide RNA generated from scaRNA, but not from snoRNA, could induce an additional pseudouridylation of U2 snRNA at position 60; both guide RNAs were equally active on a U2 ...
These non-canonical Pol II-dependent lncRNAs have snoRNA sequences at their 5′ and 3′ ends and are referred to as sno-lncRNAs. snoRNAs are 70–200 nt highly structured, nuclear-localized, protein-bound ...
Institute for Translational Medicine, The Affiliated Hospital of Qingdao University, Qingdao Medical College, Qingdao University, Qingdao, China The DNA damage repair (DDR) pathway is a complex ...
Contributed by Jeffrey L. Bennetzen, October 8, 2014 (sent for review May 8, 2014; reviewed by Bin Han and Ruiqiang Li) ...
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