Spliceosomal snRNP core assembly typically requires chaperones such as the SMN complex. Here, the authors reveal two pathways in budding yeast: a chaperone-mediated pathway involving Brr1 and Lot5 ...

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This cover highlights the article Altering metabolism programs cell identity via NAD +-dependent deacetylation by Robert A. Bone, Joshua M. Brickman and colleagues. The front cover illustration ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Multi-C 2 domain-containing ferlin proteins ...

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