Another important advantage of kidney organoids may be the capability to assess drug toxicities to other nephron segments in addition to proximal tubules. The tubular toxicants ... present study is ...

Expression of these genes localizes to the kidney, especially the proximal tubule, and correlates with muscle strength and function. In DM1 autopsy kidney tissue, characteristic ribonuclear inclusions ...

Fungi made Earth’s land liveable by building networks that released nutrients locked in primordial rock and supplied those ...

By creating the most complete and detailed genetic 'map' of kidney function to date ... iPS cell-derived kidney organoid-based proximal tubule-on-chip -- OPTECs-on-Chip -- that mimics in vivo ...

High levels of urea cause the kidneys to produce uremic toxins. Lipid nephrotoxicity could damage the structure and function of the glomerulus and tubules. Figure 2 Differentiation of Treg cells in ...

30 However, it is less conceivable how minor or transient changes in kidney function might increase MACE risk. In order to demonstrate a definite causal link between CIN and MACE, large randomised ...

Normal fluid and electrolyte levels are necessary for the whole body to function optimally. Waste materials are toxic to most of the body's cells and tissues, which results in wide-ranging symptoms.