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PNAS22d
eIF4B stimulates translation of long mRNAs with structured 5′ UTRs and low closed-loop potential but weak dependence on eIF4G
Ribosome attachment and scanning are impeded by structures in the 5′ UTR that can be resolved by RNA helicases Ded1 and eukaryotic translation initiation factor 4A (eIF4A), with cofactors eIF4B and ...
Nature17d
CBFβ-SMMHC regulates ribosomal gene transcription and alters ribosome biogenesis
CBFβ-SMMHC regulates ribosomal gene transcription. (a) Ontology analysis of genes proximate to CBFβ-SMMHC-binding sites in ME-1 cells.ChIP-seq peaks were analyzed using the Genomic Regions ...
ahajournals.org29d
Value of Bioinformatics Models for Predicting Translational Control of Angiogenesis
Department of Cellular and Molecular Pharmacology and Physiology (M.S., B.C.B.), University of Rochester School of Medicine and Dentistry, NY. Department of Medicine ...
The EMBO Journal25d
Inhibitors of eIF1A-ribosome interaction unveil uORF-dependent regulation of translation initiation and antitumor and antiviral effects
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. During translation initiation, eIF1A binds the ...
The EMBO Journal23d
A novel shuttling protein, 4E‐T, mediates the nuclear import of the mRNA 5′ cap‐binding protein, eIF4E
The eukaryotic translation initiation factor 4E (eIF4E) plays an important role in the control of cell growth. eIF4E binds to the mRNA 5′ cap structure m 7 GpppN (where N is any nucleotide), and ...
C&EN2d
Proteome-Wide Characterization of the RNA-Binding Protein RALY-Interactome Using the in Vivo-Biotinylation-Pulldown-Quant (iBioPQ) Approach
‡ Laboratory of Molecular and Cellular Neurobiology, CIBIO-Centre for Integrative Biology, University of Trento, via Delle Regole 101, 38060, Mattarello, Trento, Italy § Laboratory of Molecular ...
C&EN17d
Tertiary Interactions Determine the Accuracy of RNA Folding
Department of Chemistry and T.C. Jenkins Department of Biophysics, Johns Hopkins University, 3400 North Charles Street, Baltimore, Maryland 21218 Article Views are the COUNTER-compliant sum of full ...