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The unfavorable pharmaceutical properties of rapamycin, particularly its poor aqueous solubility and instability, preclude its clinical development as an anti-cancer agent, and, therefore, soluble ...
Multiple biochem. pathways regulate SG biol. The major signalling pathways regulating SG formation include the mammalian target of rapamycin (mTOR)-eukaryotic translation initiation factor 4F (eIF4F) ...
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