We further hypothesised that this correlates with altered intestinal epithelium paracellular integrity molecules discharged into blood as biomarkers, namely zonulin and intestinal fatty acid-binding ...

The aim of this study was to establish whether gliadin activates a zonulin dependent enterocyte intracellular signalling pathway(s) leading to increased intestinal permeability. Methods: The effect of ...

Actuality. The state of the intestinal barrier has crucial importance in the pathogenesis of celiac disease (CD).Fecal zonulin (FZ) and intestinal fatty acid binding protein (i-FABP) are important ...

Oxidative stress markers (GSH, lipid peroxides, GST, SOD, and catalase), serum zonulin, liver enzymes (ALT, AST, ALP) and renal function markers (urea nitrogen, creatinine) were investigated. ROC ...

In celiac disease patients, the most important mechanism proposed for deterioration of the gut barrier is associated with a reduction of intracellular expression of the molecule of epithelial cellular ...

Heart failure is a global health issue with significant mortality and morbidity. There is increasing evidence that alterations in the gastrointestinal microbiome, gut epithelial permeability, and ...

COVID-19 is characterized by dysregulated thrombosis and coagulation that can increase mortality in patients. Platelets are fast responders to pathogen presence, alerting the surrounding immune cells ...