3D structure of the social amoeba genome sheds light on the transition to multicellularity
Each cell of the human body contains two meters of DNA. The whole secret lies in the intricate three-dimensional arrangement that allows DNA strands to be efficiently organized and compacted within ...
In vitro reconstitution of meiotic DNA double-strand breaks: A long-standing challenge solved
In a study published in Nature, researchers report the successful in vitro reconstitution of meiotic DNA double-strand breaks ...
eLife3d
SATAY-based chemogenomic screening uncovers antifungal resistance mechanisms and key determinants of ATI-2307 and chitosan sensitivity
This important manuscript proposes a new strategy for the identification of new mechanisms of drug resistance based on SAturated Transposon Analysis in Yeast (SATAY), a powerful transposon sequencing ...