Mayo Clinic's Molecular Neurotherapeutics Lab demonstrated that maternal immune insults perturb microglial phenotypes and ...

May 21, 2025 — Researchers found that the Wnt5a protein, secreted by inflammatory fibroblasts within cancerous tumors, inhibits angiogenesis and consequently promotes hypoxia within tumors.

May 27, 2025 — A specific group of nerve cells in the brain stem appears to control how semaglutide affects appetite and weight -- without causing ... Experimental Drug May Benefit Some Patients ...

The study presents extensive gene expression profiling and bioinformatic analyses, offering insights into the roles of fibroblasts in cardiac development. The large volume of scRNA-seq data is both ...

This important study demonstrates the therapeutic potential of recombinant human PDGF-AB/BB proteins in reducing the senescent signatures of primary human intervertebral disc cells. The study ...

We first assayed whether Wnt stimulation is capable of activating JNK in cultured cells. We tested two Xenopus Wnt ligands, Xenopus Wnt5a and Xenopus Wnt8, for their activity to activate members of ...