The EMBO Journal17d
Short internal open reading frames repress the translation of N-terminally truncated proteoforms
Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Internal translation initiation sites, as ...
Which1mon
Intel processors explained: What is Core i3, i5, i7, Ultra and Pentium?
The most common brand of processor in laptops you can buy in the UK is Intel. However, Intel's myriad of marketing names for its various processors can make comparisons extremely tricky. In this guide ...
eLife3y
Pathogen invasion-dependent tissue reservoirs and plasmid-encoded antibiotic degradation boost plasmid spread in the gut
In particular, this should pertain to plasmid-encoded resistance genes encoding enzymes degrading antibiotics with an extra-cytoplasmic target (e.g. beta-lactamases). Extended spectrum beta-lactamases ...
Frontiers3y
DHAV-1 Blocks the Signaling Pathway Upstream of Type I Interferon by Inhibiting the Interferon Regulatory Factor 7 Protein
We transfected DEFs with pCAGGS-IRF7-Flag alone or cotransfected DEFs with pCMV-3C-HA and poly(I:C). Compared with that, when the IRF7 plasmid was transfected alone, the nuclear and cytoplasmic ...
eLife5y
Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions
Human cytomegalovirus (HCMV) extensively modulates host cells, downregulating >900 human proteins during viral replication and degrading ≥133 proteins shortly after infection. The mechanism of ...
Frontiers5y
Zebrafish TRIM25 Promotes Innate Immune Response to RGNNV Infection by Targeting 2CARD and RD Regions of RIG-I for K63-Linked Ubiquitination
HEK 293T cells, seeded on glass cover slips, were transfected with pCMV-Myc-zbTRIM25 and pCMV-Flag-zbRIG-I plasmids ... HEK 293T cells in 75-cm 2 flasks were co-transfected with 10 μg of different ...