Butler and colleagues found that, at each time point, patients on empagliflozin were more likely to improve KCCQ-CSS and less likely to experience deterioration (P for all < .05).

Women lost more weight than men did, 12.6% at 1 year compared with 10.2%, but otherwise had similar improvements in the Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS).

For a hierarchical composite endpoint of all-cause mortality, heart failure events, and hitting KCCQ-CSS and 6-minute walk distance thresholds, the "win" ratio was higher with semaglutide than ...

KCCQ-CSS significantly improved in both groups; the extent of improvement was greater in those with moderate to severe symptoms vs. mild symptoms (P = .02 for interaction), according to the study.

Each 10% decline in body weight was associated with a 28% lower CRP, a 14.4-meter increase in 6MWD, and a 6.4-point higher KCCQ-CSS. Conclusions ...

An analysis of a hierarchical composite endpoint (ie, death, heart failure events, change in KCCQ-CSS and 6MWD) showed that “semaglutide produced more wins than placebo” (win ratio, 1.72; 95% ...

The mean change in KCCQ-CSS from baseline to week 52 was 16.6 points with semaglutide versus 8.7 points with placebo (estimated treatment difference [ETD]: 7.8 points, 95% confidence interval [CI ...

The mean change in KCCQ-CSS from baseline to week 52 was 16.6 points with semaglutide versus 8.7 points with placebo (estimated treatment difference [ETD]: 7.8 points, 95% confidence interval [CI ...

Patients with heart failure, left ventricular ejection fraction 45% or greater, body mass index ≥30 kg/m 2, and Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS) less ...

Results presented Friday at the European Society of Cardiology (ESC) 2023 Congress in Amsterdam show that semaglutide, a once-weekly glucagon-like peptide-1 (GLP-1) receptor agonist, brought ...

Patients with heart failure, left ventricular ejection fraction ≥45%, body mass index ≥30 kg/m 2, and Kansas City Cardiomyopathy Questionnaire Clinical Summary Score (KCCQ-CSS) <90 points were ...