Background: Adoptive T-cell therapy has demonstrated impressive efficacy in hematoligical cancers but the solid tumor micro-environment presents a unique challenge. However, recently TCR-T cell ...

The initiative represents the next iteration of the Canadian Securities Administrators’ Client Relationship Model (CRM2) reforms, which further expands investment funds’ disclosure demands — by ...

Chromosomal rearrangements of the human MLL/KMT2A gene are associated with infant, pediatric, adult and therapy-induced acute leukemias. Here we present the data obtained from 2345 acute leukemia ...

Conclusions: IMA203 TCR-T was well tolerated and showed durable objective responses in patients with advanced melanoma. Given its promising risk/benefit profile and high PRAME prevalence in melanoma, ...

The partnership – which has seen a $150 million upfront payment from Novartis alongside a pledge for up to $2.1 billion in milestones – gives the Swiss pharma group rights to Monte Rosa's VAV1 ...

MRT-8102, following on the heels of our VAV1-directed MGD MRT-6160, is our second IND specifically for I&I indications, and represents the only clinical-stage MGD that selectively targets NEK7, with ...

BioNTech has found a use for some of the windfall cash it has raked in from its COVID-19 vaccine, agreeing a deal to buy Kite Pharma's entire neoantigen T cell receptor (TCR) platform for solid ...

MRT-8102, following on the heels of our VAV1-directed MGD MRT-6160, is our second IND specifically for I&I indications, and represents the only clinical-stage MGD that selectively targets NEK7 ...

You want a back story: The TCR is one of the longest-running bike models, debuting in 1997 Don't buy it if You want more aero or more comfort: The TCR is rather squeezed by Giant's Propel and Defy ...

Pulmonary hypertension (PH) describes heterogeneous population of patients with a mean pulmonary arterial pressure >20 mm Hg. Rarely, PH presents as a primary disorder but is more commonly part of ...