Here, the authors propose a new mechanism of immune tolerance. It involves the production of the immunoregulatory enzyme IDO (indoleamine 2,3-dioxygenase) induced by reverse signalling and non ...

Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by Toll-like receptors is required for intestinal homeostasis.

Up to 20% of all cancers arise in association with chronic inflammation and most, if not all, solid tumours contain inflammatory infiltrates. Immune cells have a broad impact on tumour initiation, ...

A molecular Kuhn-scale model is presented for the stress relaxation dynamics of entangled polymer networks. The governing equation of the model is given by the general form of the linearized Langevin ...

We construct global-in-time solutions for semilinear parabolic rough partial differential equations. We work on a scale of Banach spaces tailored to the controlled rough path approach and derive ...