We were unable to assay clotting-factor concentrations and pharmacokinetics (i.e., metabolism or half-life) or VKORC1 haplotype. Another limitation of this case report was our inability to conduct ...

1 Seoul National University Biomedical Informatics (SNUBI), Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Republic of Korea 2 Seoul National University ...

Purpose: The basic concepts of pharmacogenetics, pharmacogenetic study approaches, factors to consider when applying pharmacogenetic discoveries to patient care, and potential roles for ...

Département de Chimie-Biologie, Université du Québec à Trois-Rivières, C. P. 500, Trois-Rivières (Québec), G9A 5H7, Canada, and Department of Chemistry, Missouri State University, Springfield, ...

Objectives: We have observed in clinical practice that patients with fractures often have concomitant atrial fibrillation. However, it remains unclear whether atrial fibrillation increases the risk of ...

BACKGROUND: Non-variceal upper gastrointestinal bleeding (NVUGIB) secondary to peptic ulcer disease is a medical digestive emergency and could be one of the most serious adverse drug reactions.

In general, pharmacogenes are typically related to the pharmacokinetics (absorption, distribution, metabolism, excretion) of a drug or pharmacodynamics (genes that influence the response at the drug ...