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Artist's impression of a U1 adaptor oligonucleotide (orange) recruiting the U1 snRNP (snRNa in purple) to the 3' end of a target pre-mRNA (blue). Goraczniak et al. show that the resulting ...
U1 snRNP (U1), vertebrates' most abundant non-coding (spliceosomal) small nuclear RNA, silences proximal PASs and its inhibition with antisense morpholino oligonucleotides (U1 AMO) triggers widespread ...
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The recent pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) highlighted a critical need to discover more effective antivirals. While therapeutics for SARS-CoV-2 exist, ...
Although components of U2 snRNP make stable interactions with the anchoring site, this region contains no obvious conserved sequence elements (Gozani et al., 1996). Consistent with there being no ...
Jupiter Merian North American Equity Fund U1 GBP Acc . Category US Large-Cap Blend Equity. Invest. Morningstar rating. star-filled star-filled star-filled star-filled. This fund can be held in an ...
Forms that certify your benefits situation when moving within the EU . These forms are useful for exercising your rights to benefits when living and/or working in an EU country other than your own — ...
A U1 snRNP-specific assembly pathway reveals the SMN complex as a versatile hub for RNP exchange. Nat Struct Mol Biol 23, 225–230 (2016). Crossref. PubMed. Google Scholar. 40. MH Stoiber, et al., ...