The fraction of sp3-hybridized carbons (Fsp3) and the fraction of stereogenic carbons (FCstereo) are two widely employed scores of molecular complexity with strong links to biologically relevant ...

Palbociclib, deutetrabenazine (input material amorphous form with residual diffraction peaks), entinostat, risdiplam, macitentan, ibrutinib, idelalisib, duvelisib, naldemedine tosylate, and afatinib ...