CHICAGO -- Progression-free survival (PFS) in metastatic hormone receptor (HR)-positive breast cancer more than doubled with the AKT inhibitor ipatasertib added to fulvestrant after first-line ...

In amongst a clutch of discontinued phase 3 programmes in Roche's fourth-quarter results update was the news that it has stopped a study of AKT inhibitor ipatasertib as a treatment for first-line ...

Characterisation of AKT regulation in this setting will provide new strategies to combat liver cancer. Conclusions Our results highlight a fine-tuned regulation of AKT by S6K1-mediated phosphorylation ...

It is critical to identify potential cancer therapeutic targets. Aberrant activation of the PI3K/AKT/mTOR pathway has a significant role in carcinogenesis. This review summarized oncogenic ...

K-pop group Tomorrow X Together (TXT) will be having a pop-up store at Plaza Singapura from Jun. 6 to 29, 2025. Named "Ppulbatu Finding MOA", fans can purchase a selection of curated items from ...

The llms.txt file is a standardized way to provide information about how LLM-powered tools and services should interact with your documentation and codebase. This repository serves as a central hub ...

22 x 15 cm. (8.7 x 5.9 in.) ...

If a customer is running a device with Intel Trusted Execution Technology (TXT) enabled on a tenth-generation or later Intel processor with vPro support, has BitLocker enabled, and obediently ...

At the nexus of these cellular processes is the aberrant regulation of oncogenic signaling cascades such as the phosphoinositide 3-kinase and AKT (PI3K/Akt) pathway, which is one of the most ...