The next-generation KRAS G12C inhibitor MK-1084 showed promising efficacy and safety as a single agent and in combinations ...

0.82–0.89]; 120–140 mm Hg SBP TTR: 0.81 [95% CI, 0.70–0.94]; and 70–80 mm Hg diastolic BP TTR: 0.88 [95% CI, 0.83–0.93]), cardiovascular death (110–130 mm Hg SBP TTR: 0.83 [95% CI, 0.78–0.87]; 120–140 ...

Additionally, TTR gene silencing medications, patisiran and inotersen, have resulted in up to 80% reduction in TTR production, leading to stabilisation or slight improvement of peripheral neuropathy ...

they reported that only 34% of their patients with outstanding INR control (TTR ≥80%) in the first 6 months of observation continued to exhibit that degree of control over the subsequent year.8 ...

Michael Dunlop achieved the extraordinary feat of winning his 30th TT in the Monster Energy Supersport TT on Monday at the ...

Acoramidis is a selective, small molecule, orally administered, near-complete (≥90%) TTR stabilizer. These findings further support the thesis that ever better increases in serum TTR lead to ...

Federal authorities moved Friday to drop a racial discrimination lawsuit against the Sheetz convenience store chain, part of ...

This comes at a challenging time for gene therapies, as multiple serious AEs and fatalities have been recently reported.

Authorities said at least 80 shots were fired beginning at about 12:45 a.m. People reported running, ducking for cover and scrambling to their cars for safety. The crime scene spanned several ...