Most non-surgical lower back pain treatments offer little relief, with only a few showing modest benefits over placebo, an ...

According to experts, while tear gas exposure has immediate and temporary side effects like itching, blurry vision and ...

Development of TRPV1 agonists for pain isn’t a new concept, but many first-generation drugs were beset by safety issues – notably Amgen's AMG517 and Merck & Co's MK2295 ...

TRPV1 is a non-selective ligand-gated cation channel that is expressed on peripheral primary afferent sensory neurons and, when activated (by heat temperature, capsaicin, acidic pH, resinferatoxin and ...

The hypothesis tested was that paclitaxel produces these adverse effects at least in part by sensitizing transient receptor potential vanilloid subtype 1 (TRPV1) through Toll-like receptor 4 (TLR4) ...