Paradoxically, TAK1 was initially identified as a TGF-β-activated kinase 11. How can the reports of activation and inhibition of TAK1 by TGF-β be reconciled? Perhaps the answer lies in the kinetics.

Relative to the previous close share price of $1.41, Tribeca Global Natural Resources Limited's (TGF) current share price of $1.39 constitutes a movement of -$0.02 or -1.42%. Tribeca Global Natural ...

The latest Tribeca Global Natural Resources Limited [TGF] news, articles, data and analysis from The Australian Financial Review ...

Objective Extracellular matrix protein 1 (ECM1) serves as a gatekeeper of hepatic fibrosis by maintaining transforming growth factor-β1 (TGF-β1) in its latent form. ECM1 knockout (KO) causes latent (L ...

1 Introduction. Inflammatory bowel disease (IBD), which encompasses Crohn’s disease (CD) and ulcerative colitis (UC), is defined by persistent inflammation of the gastrointestinal system ().The immune ...

Recent in vitro studies have reported that sinapic acid (SPA) binds to transforming growth factor-β-activated kinase 1 (TAK1), a key regulator of inflammatory pathways. However, the hydrophobic nature ...

Perineural invasion (PNI) is a significant biological characteristic of pancreatic cancer, manifested by the infiltration of tumor cells into neural tissues, facilitating their spread and metastasis ( ...