IL-6, a key cytokine in driving inflammatory and autoimmune responses, is a compelling target to reduce irAEs through the use of IL-6 receptor (IL-6R) inhibitors. We conducted a clinical trial of 1L ...

That $102 million payroll on the Dodgers’ IL is so high that it exceeds the payroll of six teams in the league, according to Spotrac and The Athletic. Those six teams include the Cleveland ...

Objectives: The phase III RADIATE study examined the efficacy and safety of tocilizumab, an anti-IL-6 receptor monoclonal antibody in patients with rheumatoid arthritis (RA) refractory to tumour ...

Enrolled patients will receive lymphodepletion chemotherapy (fludarabine 30 mg/m 2 and cyclophosphamide 500 mg/m 2) on days -6 to -3, followed by a single dose of PRAME TCR/IL-15 NK cells on day 0.

The 6th TCR-based Therapies Summit returns as the only forum created solely for TCR experts pioneering best-in-class cell- and biologic-based approaches, to dive into T-cell receptor biology and ...

The well-studied NF-κB signaling system is a key mediator of the inflammatory response. Large-scale sequencing studies in ...