Within the immune system, interleukin-15 (IL-15) plays a relevant role by boosting the number of cytotoxic T cells and NK cells, the major drivers of anticancer immune response. Researchers from Sotio ...

to target a specific antigen on tumor cell surface. NK cells can be activated by cytokines and cytokine fusion proteins such as IL-2, IL-15, IL-12, IL-18, IL-21, ALT-803 (an IL-15 superagonist), ...

Hepatocellular carcinoma (HCC) remains an important complication of chronic liver disease, especially when cirrhosis occurs. Existing treatment strategies include surgery, loco-regional techniques, ...

1Department of Obstetrics and Gynecology, Peking University Third Hospital, China 2Institute of Medical Innovation and Research, Peking University Third Hospital, Beijing, China. 3Biobank, Peking ...

The company’s lead candidate, BMB-101, is a 5-HT2C receptor superagonist designed to address disorders like refractory epilepsy and certain neuropsychiatric conditions. The selective targeting of this ...

ImmunityBio, Inc. (NASDAQ:IBRX) is focusing on the successful commercialization of its flagship product Anktiva (nogapendekin alfa), an interleukin-15 receptor superagonist, that was approved by ...