Septerna has a market cap of $750mn and $130mn in cash and ST investments. Discover SEPN's groundbreaking drug discovery ...

Other carbohydrates can activate energy metabolism. The different mechanisms towards such effects receptor-mediated, stimulating the different signal transduction pathways.

With the strong associations established in epidemiologic studies and a dearth of evidence on the actual mechanisms by which ...

A new study shows how an anticancer drug triggers an “outside in” signal that gets it sucked into a cancer cell. The work, published Jan. 29 in Nature Communications, reveals ...

A temporally resolved CRISPR-Cas9 screen reveals DAC-induced DNA damage drives trans-cell cycle cytotoxicity that depends on ...

Scientists discover a brain pathway that helps suppress fear, offering new hope for anxiety and PTSD treatment.

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Synthetically replicating transmembrane protein signal transduction is a gaol of synthetic biology. Here, the authors show how the dimerization of synthetic transmembrane DNA receptors can be used ...

PELO–HBS1L and SKI complexes in the human mRNA quality control pathway exhibit a synthetic lethal interaction and may represent novel targets for the development of cancer therapies.

Whether you're hosting a Super Bowl party or want to connect an outdoor security system, extending your Wi-Fi signal outside doesn't have to be complicated. Trey Paul is a CNET senior editor ...

An MTF2-containing subcomplex of Polycomb Repressive Complex 2 promotes cell cycle progression through repression of D-type cyclin expression in certain cellular contexts.

Day of Atonement; the scapegoat; the eating of blood forbidden; civil and religious laws; immorality forbidden We should also forgive and choose not to remember offenses against ourselves or others.